Computational Viromics: Applications of the Computational Biology in Viromics Studies
نویسندگان
چکیده
منابع مشابه
Pharmacometabolomics Informs Viromics toward Precision Medicine
Nowadays, we are experiencing the big data era with the emerging challenge of single data interpretation. Although the advent of high-throughput technologies as well as chemo- and bio-informatics tools presents pan-omics data as the way forward to precision medicine, personalized health care and tailored-made therapeutics can be only envisaged when interindividual variability in response to/tox...
متن کاملApplications of Parameterized Computation in Computational Biology
This paper first gives an introduction to parameterized computation and complexity theory, a new subfield in theoretical computer science. Then it presents a summary of its applications to addressing some important NP-hard problems in computational biology. Specifically, we can design efficient parameterized algorithms and also drive computational lower bounds for the parameterized algorithms a...
متن کاملModern Computational Applications of Dynamic Programming
Computational dynamic programming, while of some use for situations typically encountered in industrial and systems engineering, has proved to be of much greater significance in many areas of computer science. We review some of these applications here.
متن کاملQuantitative Temporal Viromics: An Approach to Investigate Host-Pathogen Interaction
A systematic quantitative analysis of temporal changes in host and viral proteins throughout the course of a productive infection could provide dynamic insights into virus-host interaction. We developed a proteomic technique called "quantitative temporal viromics" (QTV), which employs multiplexed tandem-mass-tag-based mass spectrometry. Human cytomegalovirus (HCMV) is not only an important path...
متن کاملThe use of informativity in the development of robust viromics-based examinations
Metagenomics-based studies have provided insight into many of the complex microbial communities responsible for maintaining life on this planet. Sequencing efforts often uncover novel genetic content; this is most evident for phage communities, in which upwards of 90% of all sequences exhibit no similarity to any sequence in current data repositories. For the small fraction that can be identifi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Virologica Sinica
سال: 2021
ISSN: 1674-0769,1995-820X
DOI: 10.1007/s12250-021-00395-7